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Not Recruiting
Trial ID: NCT01619982
Effect of Pre-operative Prophylaxis With Vancomycin on Rate of Cefazolin Non-susceptible Gram Positive Surgical Site Infections in Cardiovascular Surgery Patients
Professor of Anesthesiology, Perioperative and Pain Medicine (Pediatric), Emerita
Inclusion Criteria:
1. Patient less than or equal to 1 year of age who is undergoing cardiovascular surgery
requiring CPB or patient under 18 years of age undergoing procedures involving aortic
valve or aorta
2. Patients with a positive MRSA screen or a history of MRSA infections who are
undergoing any cardiac surgery
Exclusion Criteria:
1. Patients who have known hypersensitivity to vancomycin or cephalosporins
2. Patients with renal insufficiency
3. Patients who have received vancomycin or cephalosporins 48 hours prior to the day of
surgery
4. Patients whose surgery is due to an infection-related diagnosis such as endocarditis
5. Patients whose parents do not wish to have them receive vancomycin prophylaxis
6. Neonates born at less than 38 weeks gestational age
drug: Cefazolin 25 mg/kg body weight and Vancomycin hydrochloride
drug: Cefazolin 30 mg/kg body weight
Not Recruiting
Stanford University
School of Medicine
300 Pasteur Drive
Stanford,
CA
94305
Kathleen Gutierrez, MD
650-736-7642