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Imaging Study of Chronic Low Back Pain in Patients Taking Pain Medication
Not Recruiting
Trial ID: NCT00388414
Purpose
Duloxetine has recently been shown to be effective in reducing the pain in chronic pain
patients. Duloxetine is known to exert a central mechanism, however the precise human brain
structures responsible for mediating its pain-relieving properties are not known. We will use
functional magnetic resonance imaging (FMRI) to investigate the neural and functional
correlates of pain.
Official Title
Functional MRI Neural Correlates of Medication Efficacy in Patients With Chronic Low Back Pain
Stanford Investigator(s)
Sean Mackey, M.D., Ph.D.
Redlich Professor, Professor of Anesthesiology, Perioperative, and Pain Medicine and, by courtesy, of Neurology
Eligibility
Inclusion Criteria:- Males aged 18-60
- Back Pain
- Must be able to comply with study visit schedule and other study requirements
- Capable of performing the experimental tasks Exclusion Criteria:- Contraindications
for MRI examination (e.g., metallic implants such as pacemakers, surgical aneurysm
clips, or known metal fragments embedded in the body)
- Known hypersensitivity to duloxetine or any of the inactive ingredients
- Uncontrolled narrow-angle glaucoma
Intervention(s):
drug: Placebo
drug: duloxetine
Not Recruiting
Contact Information
Stanford University
School of Medicine
300 Pasteur Drive
Stanford,
CA
94305
Neil Chatterjee
6507240522