T-Cell Project: Prospective Collection of Data in Patients With Peripheral T-Cell Lymphoma

Inclusion Criteria:

   1. Previously-untreated patients with de novo diagnosis of peripheral T-cell or NK/T-cell
   lymphoma:

      - Peripheral T-cell lymphoma unspecified;

      - Peripheral T-cell lymphoma, lymphoepithelioid variant;

      - Peripheral T-cell lymphoma, T-zone variant ;

      - Peripheral T-cell lymphoma, parafollicular variant ;

      - Angioimmunoblastic T-cell lymphoma;

      - Nasal NK/T-cell lymphoma;

      - NK/T-cell lymphoma, nasal time;

      - Anaplastic large-cell lymphoma, T/null cell, ALK+, primary systemic type

      - Anaplastic large-cell lymphoma, T/null cell, ALK-, primary systemic type

      - Anaplastic large cell lymphoma, small cell variant, ALK+

      - Anaplastic large cell lymphoma, lymphohistiocytic variant, ALK+

      - Enteropathy- type T-cell lymphoma;

      - Hepatosplenic T-cell lymphoma;

      - Peripheral gamma-delta T-cell lymphoma;

      - Subcutaneous panniculitis-like T-cell lymphoma;

      - Unclassifiable peripheral T-cell Lymphoma

      - Unclassifiable NK-cell lymphoma

   2. Age over 18

   3. Tissue biopsies adequate for diagnosis and classification and available for
   centralized review

   4. Clinical data including baseline information on disease localization and laboratory
   parameters at staging, features of treatment adopted and assurance of follow-up
   updating for at least 5 years are requested

   5. Written informed consent

Exclusion Criteria:

   1. Age < 18

   2. Diagnosis of T-cell or NK-cell leukemia or proliferation and other than mature types
   including:

      - Adult T-cell leukemia/lymphoma;

      - Blastic NK-cell leukemia/lymphoma;

      - Aggressive NK-cell leukemia

      - T-cell large granular lymphocytic leukemia

      - T-cell large granular lymphocytic proliferation

      - NK-cell large granular lymphocytic proliferation

      - T-cell prolymphocytic leukemia

      - Precursor T-cell lymphoblastic leukemia/lymphoma

      - Mycosis fungoides;

      - Sézary syndrome;

      - Primary cutaneous ALCL