Immune Mediated Disorders After Allogeneic Hematopoietic Cell Transplantation

Inclusion Criteria:

   - Planned or completed first allogeneic stem cell transplant (any conditioning regimen,
   graft source, donor type and GVHD prophylaxis regimen)

   - Signed, informed consent and, if applicable, child assent

Exclusion Criteria:

   - Inability to comply with study procedures

   - Anticipated survival less than 6 months due to co-morbid disease

   - Autoimmune disorder or inherited immunodeficiency before HCT

   - Diagnosis of late acute or chronic GVHD prior to study enrollment

   - Hematologic relapse or chemotherapy refractory disease at restaging within 1 month of
   HCT or at the time of enrollment (e.g., > 5% blasts for leukemia; poorly responsive
   lymphoma)