Trial Search Results

National Eye Institute Biorepository for Retinal Diseases

Background:

- To understand diseases of the retina and the eye, information is needed about people with and without such diseases. Researchers want to study these people and follow them over time. They also want to study body tissues and blood to understand the nature of eye disease. Studying genes, cells, and tissues may help them understand why some people get eye problems and others do not, or why some people respond to treatment while others do not. Researchers want to collect physical samples and personal data to develop a National Eye Institute database.

Objectives:

- To collect health information and blood and tissue samples from people with and without eye diseases, to be used in research studies.

Eligibility:

- Individuals of any age with different types of eye disease.

- Healthy volunteers with no history of eye disease.

Design:

- Participants may be recruited from National Eye Institute studies or may be referred from other sources.

- Participants will be screened with a physical exam and medical history. They will also have a full eye exam. Questions will be asked about family medical history, especially about eye disease.

- Blood samples will be collected. Other samples, such as saliva, tears, hair, stool, and urine, may be collected as needed. Adult participants may also provide a skin sample.

- Tissue or fluid from eye collected as part of eye care or treatment may also be added to the database.

- No treatment will be provided as part of this study.

Stanford is currently accepting patients for this trial.

Lead Sponsor:

National Eye Institute (NEI)

Stanford Investigator(s):

Eligibility


- INCLUSION CRITERIA:

Participants will be eligible if they:

   - Have the ability to understand and sign an informed consent or have a parent/legal
   guardian to do so if they are minor children.

   - Manifest diagnosed or undiagnosed retinal disease(s), or could serve as an unaffected
   control suitable for comparison to participants with various retinal diseases,
   particularly AMD and diabetic retinopathy (taking into account matching factors such
   as age and past ocular history).

EXCLUSION CRITERIA:

Participants will not be eligible if they:

   - Are unable or unwilling to give informed consent that includes collection and study of
   at least one peripheral blood sample.

   - Are unable or unwilling to give informed consent that includes use of NIH medical
   records and clinical samples for research.

   - Have a systemic disease that compromises the ability to provide adequate
   ophthalmologic examination or treatment.

Ages Eligible for Study

2 Years - N/A

Genders Eligible for Study

All

Now accepting new patients

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Recruiting