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Gastric Acid Suppression and Probiotic Colonization
Not Recruiting
Trial ID: NCT03327051
Purpose
Probiotics are over-the-counter dietary products with microorganisms that are generally
consumed for health benefit. However, the durability of these microorganisms is unclear,
particularly when they pass through the highly acidic environment of the stomach. We will
test the colonization of these microorganisms among individuals who consume probiotics with
and without acid suppression therapy.
Official Title
The Effect of Gastric Acid Suppression on Probiotic Colonization
Eligibility
Inclusion Criteria:
- Healthy volunteers ages 18 years and ≤ 75 years.
- Able to visit the study Doctor's office 3 times, answer 3 questionnaires, and provide
stools and blood samples.
Exclusion Criteria:
- Gastric cancer, Barrett's esophagus cancer, any gastrointestinal condition, or soy or
gluten sensitivity
- Previous abdominal surgery
- Currently pregnant or nursing
- Had H. Pylori Infection
- Diagnosed with any chronic medical condition other than hypertension or hyperlipidemia
- Currently consuming herbs or probiotics
Intervention(s):
drug: Omeprazole
dietary supplement: VSL #3
drug: Placebo
Not Recruiting
Contact Information
Stanford University
School of Medicine
300 Pasteur Drive
Stanford,
CA
94305
Berkeley Limketkai
650-736-0431