Trial Search Results

Comparing Diuretic Strategies in Hospitalized Heart Failure

We will conduct a pragmatic randomized trial comparing whether using a combination of two types of diuretics (loop + thiazide) compared with using a single diuretic (loop only) will result in shorter hospital stays for patients hospitalized with heart failure.

Stanford is currently not accepting patients for this trial.

Lead Sponsor:

Stanford University

Collaborator: American Heart Association

Stanford Investigator(s):


  • Drug: Loop Diuretics vs. loop + thiazide diuretics


Phase 4


Inclusion Criteria:

Any adult (age ≥18 years) admitted to the Heart Failure Service at Stanford Health Care
with an indication for treatment with a diuretic.

Exclusion Criteria:

   1. admission to the intensive care unit or cardiac care units

   2. maintenance dialysis on admission

   3. any mechanical circulatory support on admission

   4. history of heart transplant

   5. allergy / intolerance to loop or thiazide diuretics

   6. admission serum sodium < 125 meq/L (from EPIC)

   7. admission serum potassium < 3.0 meq/L (from EPIC)

Ages Eligible for Study

18 Years - N/A

Genders Eligible for Study


Not currently accepting new patients for this trial

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Tara Chang, MD, MS
Not Recruiting