Decellularized, Whole Donor Nipple-Areola Complex Reconstruction Grafts

Inclusion Criteria:

   - Patient age 18-65

   - Patient desires NAC grafting ≥3 months after autologous breast reconstruction

   - Patient agrees to sleep on back until grafts healed (6 weeks)

   - Patient agrees to abstain from aspirin, alcohol, or excessive caffeine until grafts
   healed (6 weeks)

   - Patient agrees to not undergo NAC tattooing until completing study (12 months)

   - Patient is able to understand and willing to sign informed consent.

Exclusion Criteria:

   - History of delayed wound healing

   - history of Vitamin C deficiency

   - history of diabetes (Type I or Type II)

   - current BMI<18.5 or >40 kg/m,

   - patient has any other uncontrolled comorbidity.

   - Patient has a history of allergic reaction to any decellularized biologic matrix
   product.

   - Patient is currently smoking or using tobacco or nicotine products (i.e. patch, gum,
   or nasal spray) or has used such products in the past 12 months.

   - Patient is currently receiving radiation or chemotherapy or received radiation to the
   breast wall.

   - Patient has a history of prior NAC reconstruction

   - Patient has had NAC tattooing.

   - Patient is pregnant, breastfeeding or planning to become pregnant during the study
   period.