Trial Search Results

Avexitide Safety and Efficacy to Treat Acquired Hyperinsulinemic Hypoglycemia

The primary goal of this study is to evaluate the safety and efficacy of two different dosing regimens of an investigational drug called Avexitide in treating low blood sugar in patients with Acquired Hyperinsulinemic Hypoglycemia.

Stanford is currently accepting patients for this trial.

Lead Sponsor:

Dr. Tracey McLaughlin, MD

Collaborator: Eiger BioPharmaceuticals

Stanford Investigator(s):

Intervention(s):

  • Drug: Avexitide

Phase:

Phase 2

Eligibility


Inclusion Criteria:

   - History of bariatric or upper-gastrointestinal surgery (RYGB, VSG, gastrectomy,
   esophagectomy, or Nissen fundoplication) at least 12 months prior to the start of
   Screening

   - History of recurrent hypoglycemia occurring after bariatric or upper-GI surgery, as
   documented in the medical record.

   - Body mass index (BMI) of up to 40 kg/m2

   - If female, must not be breastfeeding and must have a negative urine pregnancy test
   result

Exclusion Criteria:

   - Major surgery within 6 months before randomization.

   - History of or current hyperinsulinism other than Acquired Hyperinsulinism (e.g.,
   insulin autoimmune hypoglycemia).

   - Use of agents that may interfere with glucose metabolism

Ages Eligible for Study

18 Years - N/A

Genders Eligible for Study

All

Now accepting new patients

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Termeh Shamloo
650-721-1300
Recruiting