Trial Search Results

Gastroparesis Registry 2

To expand a registry of patients for the study of the epidemiology, etiology, and degree of morbidity associated with gastroparesis.

Stanford is currently not accepting patients for this trial.

Lead Sponsor:

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Stanford Investigator(s):

Eligibility


Inclusion Criteria:

   - Symptoms of gastroparesis of at least 12 weeks duration (do not have to be contiguous)
   with varying degrees of nausea, vomiting, early satiety, post-prandial fullness,
   and/or abdominal pain

   - An etiology of either diabetic, idiopathic, or post-Nissen fundoplication
   gastroparesis

   - Gastric emptying scintigraphy of solids and liquids test using 4 hours Egg Beaters®
   protocol within the last 6 months with either:

      - Abnormal gastric emptying rate defined as an abnormal 2 hour (>60% retention)
      and/or 4 hour (>10% retention) result based on a 4-hour scintigraphic low fat Egg
      Beaters® gastric emptying study performed at a GpCRC clinical center.

      - Patients with a normal gastric emptying rate but with symptoms of gastroparesis
      may be enrolled and classified as possible gastroparesis or gastroparesis-like
      with normal gastric emptying

   - Age at least 18 years at initial screening visit

   - Upper endoscopy results within last 2 years

Exclusion Criteria:

   - Inability to comply with or complete the gastric emptying scintigraphy test (including
   allergy to eggs)

   - Presence of other conditions that could explain the patient's symptoms:

   - Pyloric or intestinal obstruction as determined by endoscopy, upper GI series or
   abdominal CT scan

   - Active inflammatory bowel disease

   - Known eosinophilic gastroenteritis

   - Primary neurological conditions that could cause nausea and/or vomiting such as
   increased intracranial pressure, space occupying or inflammatory/infectious lesions

   - Acute liver failure

   - Advanced liver disease (Child's B or C; a Child-Pugh-Turcotte (CPT) score of ≥7 )

   - Acute renal failure

   - Chronic renal failure (serum creatinine >3 mg/dL) and/or on hemodialysis or peritoneal
   dialysis

   - Total or subtotal (near complete) gastric resection, esophagogastrostomy,
   gastrojejunostomy, or gastric bypass. Note: patients with prior fundoplication will be
   eligible for enrollment.

   - Any other plausible structural or metabolic cause

   - Any other condition, which in the opinion of the investigator would interfere with
   study requirements

   - Inability to obtain informed consent

Ages Eligible for Study

18 Years - N/A

Genders Eligible for Study

All

Not currently accepting new patients for this trial

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Linda Nguyen, MD
650-725-3362
Not Recruiting