Trial Search Results

Open-label Pilot Clinical Trial of Oral Ivermectin to Treat Atopic Dermatitis

This pilot trial studies how well a novel oral therapeutic agent performs to treat patients with atopic dermatitis, particularly facial dermatitis.

Stanford is currently not accepting patients for this trial.

Lead Sponsor:

Stanford University

Stanford Investigator(s):

Intervention(s):

  • Drug: Ivermectin Pill

Phase:

Phase 2

Eligibility


Inclusion Criteria:

   1. Must have at least one lesion of atopic dermatitis (At least 1% Body surface Area).

   2. 18 years of age or older.

   3. Must be willing to take oral ivermectin once weekly for 4 weeks and monitor over 8
   weeks.

   4. For women of child bearing potential, a negative urine pregnancy test

   5. Women of child bearing potential are expected to use an effective method of birth
   control while participating in the study and for 1 month after taking the last dose.

   6. For male subjects with female partners of childbearing potential, agreement to use
   adequate contraception while participating in the study and for 1 month after taking
   the last dose.

   7. Has signed and dated the current Institutional Review Board approved informed consent
   document.

   8. Must be able to read and speak English fluently.

Exclusion Criteria:

   1. Is currently participating or has participated in another interventional clinical
   study in the past 2 weeks;

   2. Is age <18 years old.

   3. Has had known or previous hypersensitivity or allergic reactions to oral ivermectin
   before;

   4. Has an immunologic or infectious disease (e.g. hepatitis, tuberculosis, HIV or AIDS,
   lupus rheumatoid arthritis) which could place the subject at risk or interfere with
   the accuracy of the study results;

   5. Taking any medication known to interact with ivermectin like Dasabuvir (theoretical)
   or warfarin (probable).

   6. Is planning a trip to a sunny climate, to use tanning booths or use other UV sources
   throughout the course of this study;

   7. Has a history of hypersensitivity to any substance in investigational preparation;

   8. Has any clinically significant medical condition or laboratory abnormality that would,
   in the opinion of the Investigator, put the patient at undue risk or interfere with
   the interpretation of the study results;

   9. Is currently pregnant or breastfeeding.

10. Has other skin conditions that might interfere with Atopic Dermatitis diagnosis and/or
   evaluation (i.e. psoriasis current active viral, bacterial and fungal skin infections)
   as assessed by the Investigator;

11. Any other condition or factor the Investigator or their duly assigned representative
   believes may affect the ability of the subject to complete the study or the
   interpretation

12. History of congestive heart failure; cardiac arrhythmias; or other findings of
   ventricular dysfunction.

13. History of current evidence of malabsorption or liver disease.

14. Cannot read and speak English fluently.

15. Does not have at least 1% body surface area with lesional atopic dermatitis

Ages Eligible for Study

18 Years - 80 Years

Genders Eligible for Study

All

Not currently accepting new patients for this trial

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Facility Contact
650-723-6316
Not Recruiting