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TRIAD - Treatment of Insomnia and Depression
Not Recruiting
Trial ID: NCT00767624
Purpose
The aim of the proposed three-site study is to increase the rate of full remission from major
depressive disorder (MDD) at the end of 16 weeks of treatment for people who experience both
major depressive disorder and insomnia.
Official Title
Improving Depression Outcome by Adding Insomnia Therapy to Antidepressants
Stanford Investigator(s)
Rachel Manber, PhD
Professor of Psychiatry and Behavioral Sciences (General Psychiatry and Psychology-Adult)
Eligibility
Inclusion Criteria:
1. Meets criteria for Major Depressive Disorder
2. Between 18 and 75 years of age and adequately fluent in English
3. Meets criteria for an insomnia disorder
Exclusion Criteria:
1. Women who are currently pregnant, breast-feeding, or not using a reliable birth
control method.
2. People for whom the antidepressant medication(s) provided in the study is not
indicated
3. People who have had minimum adequate trials of (or have not been able to tolerate) all
three study medications.
4. People with uncontrolled medical conditions.
5. People with moderate or severe sleep disorders other than insomnia
6. Individuals on a fixed night shift or rotating work schedule that requires a night
shift.
7. Patients with a current principal diagnosis of a psychiatric disorder that
necessitates treatment that is not offered in the study.
Intervention(s):
drug: Antidepressant
behavioral: Desensitization Therapy for Insomnia
behavioral: Cognitive Behavioral Therapy for Insomnia
Not Recruiting
Contact Information
Stanford University
School of Medicine
300 Pasteur Drive
Stanford,
CA
94305