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Reading in Preterm and Full-term Children: Neural Basis and Prediction
Not Recruiting
Trial ID: NCT01599546
Purpose
The purpose of this study is to understand reading abilities of children born preterm: their
cognitive profiles, the neural basis of good and poor reading abilities, and the behavioral
and neural factors that predict persistent difficulties. The investigators hope to learn
- what specific skills correlate reading skills
- if preterm children have different cognitive profiles than full term children with
respect to reading
- if cognitive skills measured in kindergarten predict reading ability in the second grade
- if parts of the brain are associated with reading skill
- whether brain characteristics in kindergarten predict reading in second grade.
Official Title
Reading in Preterm and Full-term Children: Neural Basis and Prediction
Eligibility
Inclusion Criteria:
- Pre-terms: PT children born <35 weeks gestation and weighing <2000 grams at birth.
- Full-term: FT participants will be healthy children born ≥ 36 weeks gestation and
weighing ≥ 2750 grams, who are developing typically per pediatrician well-visit report
and match the PT group on age, gender, and SES.
Exclusion Criteria:
- Congenital anomalies or recognizable malformation syndromes
- Mother's self-reported use of illicit drugs or alcohol during pregnancy;
- Birth weight <3rd %tile (small for gestational age, SGA) according to gestational age
specific growth curves;
- Serious neurological problems including active seizure disorder (afebrile seizure
within the last year) and/or anticonvulsant medication use, history of a central
nervous system infections, or ventriculoperitoneal shunt for treatment for
hydrocephalus
- IQ < 70 on the testing of this study because we would expect language delays in this
group;
- Sensori-neural hearing loss, defined as 4-tone pure-tone average > 25 decibels as
assessed at any time because hearing loss compromises language and reading
development;
- Visual impairments that would interfere with the ability to read; (8) presence of any
other health condition that might compromise academic functioning (FT only).
- Any child who has not been learning English either at home or at school for at least 2
years
Not Recruiting
Contact Information
Stanford University
School of Medicine
300 Pasteur Drive
Stanford,
CA
94305
Vanessa N Durand, BA
650-498-7690