Trial Search Results

Pilot Study to Evaluate MR-guided Laser Ablation of Focal Lesions in Patients With Medically Refractory Partial Epilepsy

To investigate whether MR-guided laser induced thermal therapy in patients diagnosed with focal lesional epilepsy using the Visualase Thermal Therapy System is both a feasible and safe minimally invasive technique for control of seizures in such patients.

Stanford is currently not accepting patients for this trial.

Lead Sponsor:

Mayo Clinic

Stanford Investigator(s):

Intervention(s):

  • Procedure: Laser ablation

Phase:

Phase 1

Eligibility


Inclusion Criteria:

   - Age 18 years or older at entry to protocol.

   - History of MRI lesional-related epilepsy for at least one year.

   - Failure to respond to more than 2 anti-epileptic drugs at adequate dose and duration.

   - Candidate for resective epilepsy surgery.

   - Considered healthy enough to undergo surgery with general anesthesia.

   - The patient has given written informed consent after the nature of the study and
   alternative treatment options have been explained.

   - Must have 3 months of seizure frequency recorded prior to procedure.

Exclusion Criteria:

   - Presence of any non-MRI compatible implanted electronic device.

   - Presence of a metallic prosthetic or implant including artificial hips, knees, joints,
   or rods and screws.

   - Active Major depression

   - History of Suicide attempts

   - History of Non-Epileptic Behavioral Spells

Ages Eligible for Study

18 Years - 75 Years

Genders Eligible for Study

All

Not currently accepting new patients for this trial

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
William Marshall
(650) 723-6767
Recruiting