Trial Search Results

Preventing HIV Among Native Americans Through the Treatment PTSD & Substance Use

Investigators will conduct a two-arm, comparative effectiveness randomized controlled trial of two culturally adapted, empirically based programs (EBP) - Narrative Exposure Therapy (NET) vs. Motivational Interviewing with Skills Training (MIST) in terms of lowering HIV sexual-risk behaviors (HSB) for American Indian / Alaska Native (AIAN) men and women. NET addresses Posttraumatic Stress Disorder (PTSD) as a pathway to preventing substance use disorders (SUD) and HSB whereas MIST addresses substance misuse as a way of preventing SUD and HSB.

Stanford is currently accepting patients for this trial.

Lead Sponsor:

University of Washington

Collaborator: National Institute on Minority Health and Health Disparities (NIMHD)

Stanford Investigator(s):


  • Behavioral: Narrative Exposure Therapy (NET)
  • Behavioral: Motivational Interviewing w/Skills Training (MIST)




Inclusion Criteria:

   - 16 years old or older

   - Native American

   - At least sub-threshold PTSD

   - Substance use in the previous 12 months

   - Any lifetime sexual activity

Exclusion Criteria:

   - Suicidal ideation, plan, or attempt in the previous 30 days

   - Homicidal ideation in the previous 3 months

   - Psychiatric medication that has not been stable for at least 2 months

   - A DSM-5 alcohol dependence diagnosis with severe withdrawal symptoms

Ages Eligible for Study

16 Years - N/A

Genders Eligible for Study


Now accepting new patients

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305