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Understanding and Testing Recovery Processes for PTSD and Alcohol Use Following Sexual Assault
Not Recruiting
Trial ID: NCT04124380
Purpose
Sexual assault can lead to devastating consequences including the development of chronic
conditions including posttraumatic stress disorder (PTSD) and alcohol use disorders (AUD).
Interventions delivered soon after exposure to assault can decrease the long-term negative
consequences of sexual assault but existing interventions are limited in their ability to
target concurrent PTSD symptoms and alcohol use and little is known about how to make best
practice treatment decisions in the early period following sexual assault. A greater emphasis
on transdiagnostic processes that are related to both PTSD and alcohol use, such as fear and
reward systems, can elucidate mechanisms of recovery, lead to the development of more
effective intervention approaches, and guide clinical decision making for patients recently
exposed to sexual assault.
Official Title
Understanding and Testing Recovery Processes for PTSD and Alcohol Use Following Sexual Assault
Stanford Investigator(s)
Debra Lee Kaysen
Professor of Psychiatry and Behavioral Sciences (Public Mental Health & Population Sciences)
Eligibility
Inclusion Criteria:
1. Identifies as female.
2. Between the age of 18 and 65.
3. Reports a sexual assault in the last 4 weeks to 1 year.
4. Current PTSD severity of 23+ on the PSS-I-5.
5. Current heavy alcohol use (2+ heavy episodic drinking occasions [4+ drinks on one
occasion] in past month).
6. Access to the internet and a device with a webcam.
Exclusion Criteria:
1. Current diagnosis of schizophrenia, delusional disorder, or organic mental disorder as
defined by the DSM-5.
2. Current diagnosis of bipolar disorder, depression with psychotic features, or
depression severe enough to require immediate psychiatric treatment (i.e., serious
suicide risk with intent and plan).
3. Unwilling or unable to discontinue current trauma-focused psychotherapy or current
substance use psychotherapy.
4. Unstable dose of psychotropic medications in the prior 3 months.
5. Ongoing intimate relationship with the perpetrator of most recent assault.
6. Current diagnosis of a severe substance use disorder according to DSM-5, other than
alcohol in the last month.
7. No clear trauma memory.
8. Current higher dose use of benzodiazepines (greater than the equivalent of 4 mg of
lorazepam, 2 mg alprazolam, 1.5 mg clonazepam, or 20 mg of diazepam).
Intervention(s):
behavioral: Imaginal Exposure
behavioral: Alcohol Skills Training
behavioral: Supportive Telehealth
Not Recruiting
Contact Information
Stanford University
School of Medicine
300 Pasteur Drive
Stanford,
CA
94305