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PET/MRI in the Diagnosis of Pediatric Chronic Pain
Recruiting
Trial ID: NCT04435821
Purpose
[18F]FTC-146 is a sigma-1 receptor detector and is an experimental radiotracer. Several
studies have implicated involvement of sigma-1 receptors in generation and perpetuation of
chronic pain conditions, while others are investigating anti sigma-1 receptor drugs for
treatment of chronic pain. Using [18F]-FTC-146 and PET/MRI, we hope to learn what is the best
approach to identify the source of pain generation and characterize the disease in pediatric
patients with chronic pain.
Official Title
Use of PET/MRI in the Diagnosis of Pediatric Chronic Pain
Stanford Investigator(s)
Helen Nadel
Clinical Professor, Radiology - Pediatric Radiology
Eligibility
Inclusion Criteria:
- 11-18 years old.
- Chronic pain (nociceptive, neuropathic or mixed pain) lasting at least 2 months.
- Pain level of at least 4/10 on a 0-10 Comparative Pain Scale (reported at time of
screening).
- Covid Vaccination status: Vaccinated or unvaccinated subjects who received a negative
test result from the Covid test within 72 hours of the scan.
Exclusion Criteria:
- MRI incompatible
- Pregnant or nursing
- Non-English speaker
- Claustrophobic
Intervention(s):
drug: [18F]FTC-146
Recruiting
Contact Information
Stanford University
School of Medicine
300 Pasteur Drive
Stanford,
CA
94305