Trial Search Results

Confirming the Efficacy/Mechanism of Family Therapy for Children With Low Weight ARFID

This study is examining the efficacy and mechanism of family therapy compared to usual care for children between the ages of 6 and 12 who are diagnosed with Avoidant/Restrictive Food Intake Disorder. Preliminary data suggest that family therapy is superior to usual care and that improvement in parental self-efficacy related to feeding their children is the mechanism of treatment. In addition, this study will attempt to identify specific patient groups who respond to family therapy.

Stanford is currently accepting patients for this trial.

Lead Sponsor:

Stanford University

Collaborator: National Institutes of Health (NIH)

Stanford Investigator(s):

Intervention(s):

  • Behavioral: Family-based Treatment for ARFID
  • Behavioral: Manualized Non-Specific Usual Care for ARFID

Phase:

N/A

Eligibility


Inclusion Criteria:

   - Children meeting DSM-V criteria for ARFID

   - Children between the ages of 6 to 12 years old, living with their families

   - Medically stable for outpatient treatment according to the recommended thresholds of
   the American Academy of Pediatrics and the Society of Adolescent Medicine.

   - Not engaging in another individual or family-based psychotherapy trial during the
   duration of treatment sessions in the study.

   - Less than 4 sessions of FBT

   - If taking medication for co-morbid disorders, participants must be on a stable dose of
   medication for 8 weeks (2 months) before participating. If the participant is on a new
   medication at baseline, but is discontinuing the medication in order to start the
   study, they must have discontinued the medication before beginning treatment.

   - EBW between 75% and 88%.

   - Able to fluently speak and read English

Exclusion Criteria:

   - Current physical, psychotic illness or other mental illness requiring hospitalization

   - Current psychotic illness or mental retardation or other mental illnesses that would
   prohibit the use of psychotherapy

   - Current dependence on drugs or alcohol

   - Physical conditions (e.g. diabetes mellitus, pregnancy) known to influence eating or
   weight

   - Any medical complications or severe mental disorder (psychosis, low-functioning
   Autism) that may reduce compliance with the study procedures or require more intensive
   care to manage the symptoms

   - 4 or more sessions of FBT

   - Currently taking medication for co-morbid disorders that cannot be safely discontinued
   or prescribed for less than 2 months

   - Medically unstable for outpatient treatment according to the recommended thresholds of
   the American Academy of Pediatrics and the Society of Adolescent Medicine, defined as:
   vital sign instability (heart rate less than 45 beats per minute), clinically
   significant orthostatic blood pressure with changes usually greater than 35 points or
   findings of gastrointestinal bleeding, dizziness, or syncope, IBW <75%, hypothermia
   (body temperature less than 36 degrees centigrade), clinically significant electrolyte
   abnormalities, or prolonged QTc on electrocardiogram

   - Expected Body Weight (EBW) <75% or > 88%

   - Unable to fluently speak and read English

   - Parent excluded

   - Suicidal

   - In the case of patients with current, or a history of sexual or physical abuse by
   family members, perpetrators of the abuse will be excluded from treatment.

Ages Eligible for Study

6 Years - 12 Years

Genders Eligible for Study

All

Now accepting new patients

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Kyra Citron, BA
650-723-9182
Recruiting