Trial Search Results

Telehealth 2.0: Evaluating Effectiveness and Engagement Strategies for CPT-Text for PTSD

There is a pressing need to increase capacity to treat PTSD related to or exacerbated by the COVID-19 pandemic. Texting-based therapy holds promise to increase capacity and reduce barriers to delivering evidence-based treatments (EBTs), but ongoing engagement in digital mental health interventions is low. This study will compare a texting-based EBT for PTSD to culturally-informed texting-based treatment for PTSD as usual, and it will also compare a unique incentive strategy to typical platform reminders aimed to prevent early discontinuation in therapy.

Stanford is currently accepting patients for this trial.

Lead Sponsor:

Stanford University

Collaborator: The University of Texas Health Science Center at San Antonio

Stanford Investigator(s):


  • Behavioral: CPT-Text
  • Behavioral: Culturally Informed Trauma Treatment (CITT)
  • Behavioral: Retention Incentive
  • Behavioral: Reminder as Usual




Inclusion Criteria:

   - Over the age of 18 residing in the United States

   - Criterion A event measured by the Life Events Checklist for DSM-5 (LEC-5)

   - Significant symptoms of PTSD as evidenced by a score of 33 or above on the PCL-5

   - PTSD symptoms that began or increased during the COVID pandemic (per self-report)

   - Registered/registering on Talkspace for messaging-based therapy

   - Ownership of a personal device for texting

   - Residence in a state with therapist capacity on the Talkspace platform

Exclusion Criteria:

   - Acute risk for suicidal thoughts and/or behaviors measured by the Columbia Suicide
   Severity Rating Scale Lifetime-Recent Screen

   - Psychosis or substance abuse that requires prioritization of treatment and/or higher
   level of care

Ages Eligible for Study

18 Years - 75 Years

Genders Eligible for Study


Now accepting new patients

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Shannon Wiltsey Stirman, PhD