Prostatic Artery Embolization for the Treatment of Lower Urinary Tract Symptoms in Prostate Cancer Patients Undergoing Radiation Therapy

Inclusion Criteria:

   - Age ≥ 40 years and ≤ 90 years old

   - Prostate volume ≥ 40 mL and ≤ 300 mL

   - Biopsy proven prostate cancer undergoing radiation therapy

   - Diagnosis of moderate to severe lower urinary tract symptoms (LUTS) defined as at
   least one of the following:

      1. IPSS ≥ 12 or dependent on urinary catheterization, or

      2. IPSS Quality of Life (QoL) assessment ≥ 3, and

      3. Qmax ≤ 12 mL/sec

   - Ability to understand and willingness to sign the written consent

Exclusion Criteria:

   - Neurogenic bladder disorder due to multiple sclerosis, Parkinson's disease, spinal
   cord injury, diabetes, etc., as demonstrated on urodynamic testing.

   - Detrusor muscle failure, urethral stenosis, or urinary obstruction due to causes other
   than prostatic obstruction, as demonstrated on urodynamic testing

   - Bladder diverticula greater than 5 cm or bladder stones greater than 2 cm

   - Other active urogenital cancer

   - Baseline serum creatinine greater than 2 mg/dL

   - Evidence of tortuous or atherosclerotic blood vessels

   - Coagulation disturbances not normalized by medical treatment

   - Allergy to iodinated contrast agents not responsive to steroid premedication regimen