Mobile Technology-Based System for Patient Engagement and Physician-Directed Remote Management of Heart Failure

Inclusion Criteria:

   - Age ≥ 18

   - Diagnosis of heart failure

   - Most recent left ventricular ejection fraction ≤ 40% in the prior year based on
   echocardiogram, MRI, CT, or nuclear perfusion

   - Primary cardiologist enrolled in the study

   - Currently admitted with upcoming discharge or discharged from hospital within the
   prior 2 weeks

   - At least two eligible heart failure therapies (guideline-recommended BB, RASI, MRA, or
   SGLT2i) not yet initiated or on ≤ 50% of target dose

Exclusion Criteria:

   - Receives dialysis

   - Inotropic therapy during hospitalization

   - History of heart transplant or actively listed on heart transplant waiting list

   - History of left ventricular assist device implantation

   - Cardiac amyloidosis

   - Pregnant or currently trying to be pregnant

   - Life expectancy estimated less than 6 months related to non-cardiac comorbidities as
   per investigator's judgement

   - Actively enrolled in hospice or comfort care

   - Currently participating in an investigational device or drug study or having
   participated in such a study within 30 days prior to screening

   - Subject or their caregiver without a smartphone

   - Subject or their caregiver not proficient with written and spoken English

   - Subject unavailable to complete all study procedures (e.g., interviews) to the best of
   the subject and investigator's knowledge

   - Any other disorder or condition that, in the opinion of the investigator would pose a
   risk to subject safety or interfere with the study evaluation, procedures or
   completion

   - Subject has diminished decision-making capacity

   - Planned discharge to skilled nursing facility