Investigating Two rTMS Strategies to Treat Cannabis Use Disorder

Inclusion Criteria:

   1. Participants must be able to provide informed consent and function at an intellectual
   level sufficient to allow accurate completion of all assessment instruments.

   2. Participants must be between the ages of 18 and 60.

   3. Participants must meet DSM-5 criteria for at least moderate Cannabis Use Disorder,
   with use of at least 20 out of the last 28 days.

   4. Participants must express a desire to reduce cannabis use or quit.

   5. Participants must have a positive UDS for cannabis during their enrollment visit
   (confirming they are regular users).

   6. The investigative team must believe each participant is a good study-candidate.

Exclusion Criteria:

   1. Participants must not be pregnant or breastfeeding.

   2. Participants must not meet moderate or severe use disorder of any other substance with
   the exception of tobacco/nicotine.

   3. Participants must not be on any medications that have central nervous system effects
   that have changed in the past 4-weeks.

   4. Participants must not have a history of/or current psychotic disorder or bipolar
   disorder.

   5. Participants must not have any other Axis I condition requiring current treatment.

   6. Participants must not have a history of Dementia or other cognitive impairment.

   7. Participants must not have active suicidal ideation, or a suicide attempt within the
   past 180 days.

   8. Participants must not have any contraindications to receiving rTMS or MRI (e.g. metal
   implanted above the head, history of seizure, any known brain lesion).

   9. Participants must not have any unstable general medical conditions.