A Pilot Trial of Adalimumab for the Treatment of Osteoarthritis

Not Recruiting

Trial ID: NCT00185562

Purpose

A 12 week trial of Adalimumab in subjects with active erosive inflammatory OA who have ahd an inadequate response to NSAID therapy

Official Title

A Pilot Trial of Adalimumab for the Treatment of Osteoarthritis

Stanford Investigator(s)

Mark Genovese
Mark Genovese

James W. Raitt M.D. Professor, Emeritus

Eligibility


Inclusion Criteria:

   - Age 45 or older, >/=2 tender and 2 swollen joints, inadequate response to NSAID
   therapy, hand radiographs with evidence of erosive changes, acceptable form of birth
   control

Exclusion Criteria:

   - Autoimmune arthropathy, History of psoriasis, Previous TNF therapy, current use of any
   DMARD, evidence of TB, history of Hep C, B, or HIV

Intervention(s):

drug: Adalimumab

Not Recruiting

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305