Assessment of Pain in People With Thalassemia Who Are Treated With Regular Blood Transfusions

Not Recruiting

Trial ID: NCT00872833


Thalassemia is an inherited blood disorder that can result in mild to severe anemia. Regular blood transfusions, which refresh the healthy red blood cell supply, are one treatment for thalassemia. People with thalassemia often experience pain, but the exact source of pain remains unknown. This study will examine how pain varies during the blood transfusion cycle in people with thalassemia who are treated with regular blood transfusions.

Official Title

Assessment of Pain in Transfusion Dependent Patients With Thalassemia During Transfusion Cycles

Stanford Investigator(s)

Maurice L. Druzin
Maurice L. Druzin

Professor of Obstetrics and Gynecology (Maternal Fetal Medicine) and, by courtesy, of Pediatrics


Inclusion Criteria:

   - Participating in the Thalassemia Clinical Research Network Assessment of Pain study

   - Has a transfusion dependence of at least eight transfusions per year

   - Diagnosis of beta thalassemia or E-beta-thalassemia

   - Experiences at least "mild" pain in the 1 month before study entry, as measured by the
   response to the Brief Pain Inventory (BPI) question #6 from the Assessment of Pain

Exclusion Criteria:

   - Unwillingness or inability to complete the Brief Pain Inventory Short Form (BPI-SF) on
   a daily basis

Not Recruiting

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305