A Pilot Study of "Stanford Proxy Test for Delirium" (S-PTD)

Not Recruiting

Trial ID: NCT03954769


Although there are several tools available for the screening of delirium among the medically ill, they all have some limitations. First, none of the available tools have been validated against newly developed and published DSM-5 (Diagnostic and Statistical Manual) or ICD-10 (International Statistical Classification of Diseases and Related Health Problems) criteria. Additionally, all the screening/diagnostic tools presently available have the same limitation, they all require significant patient involvement and participation (e.g., questions and activities) in order to complete the assessment. By definition, delirium is a neuropsychiatric disorder characterized by disturbance in attention and awareness, and additional disturbance in cognition (e.g., memory deficit, disorientation), language, visuospatial ability, or perception. The intrinsic characteristics of delirium seem to interfere with the patient's ability to participate and complete many of the tasks associated with delirium evaluation itself. Finally, most available tools seem to narrowly focus on some neurocognitive areas of delirium, but not being comprehensive enough. In contrast, the S-PTD is designed so it can be completed by the nursing staff caring for the patients, the medical personnel most intimately involved with the care and aware of the behaviors exhibited by the patient during the course of their hospital stay. The idea is that nurses will complete the screening tool (hence the term "by proxy"), based on the behaviors and interactions observed during the course of a conventional "nursing shift", to determine whether the patient meets current neuropsychiatric criteria for the diagnosis of delirium.

Official Title

A Pilot Study of the Psychometric Properties of the "Stanford Proxy Test for Delirium" (S-PTD): a New Screening Tool for the Detection of Delirium

Stanford Investigator(s)

Jose R. Maldonado, MD, FACLP, FACFE
Jose R. Maldonado, MD, FACLP, FACFE

John and Terry Levin Family Professor of Medicine and Professor, by courtesy, of Emergency Medicine and of Medicine


Inclusion Criteria:

   - Inclusion criteria for enrolled patients:

      - all inpatients admitted to Stanford Hospital's selected general medical and
      surgical units

      - patients must be able to communicate and read English and/or Spanish

      - ages 18 and older

   - Inclusion criteria for enrolled nurses:

      - All nurses assigned to each enrolled patient for the shift during which that
      patient is enrolled, will be invited to participate in the study to assess the
      tool's acceptability and ease of use.

Exclusion Criteria:

   - For enrolled patients:

      - unable to speak English or Spanish.

      - unwillingness to participate in the study

      - for patients who are unable to consent (i.e., lack capacity), either the lack of
      availability of a suitable surrogate or the surrogate's unwillingness to provide

   - For enrolled nurses: unwillingness to participate in the study.

Not Recruiting

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305