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Bone Marrow Sparing Image-Guided Radiation Therapy (RT) Incorporating Novel Use of GCSF and FDG-PET Imaging
Recruiting
I'm InterestedTrial ID: NCT04514692
Purpose
This is a research study using Granulocyte Colony Stimulating Factor (GCSF) as a bone marrow
stimulating agent for imaging to guide radiation treatment planning. G-CSF is a type of
growth factor. Growth factors are proteins made in the body. G-CSF is a type of growth factor
that makes the bone marrow produce white blood cells to reduce the risk of infection after
some types of cancer treatment.
Official Title
Phase 1 2 Study of Individualized Bone Marrow Sparing Image Guided Radiotherapy Incorporating Novel Use of Granulocyte Colony Stimulating Factor and FDG PET Imaging
Stanford Investigator(s)
Elizabeth Kidd
Associate Professor of Radiation Oncology (Radiation Therapy)
Eligibility
Inclusion Criteria:
- 2018 international Federation of Gynecology and Obstetrics (FIGO) stage I IIIC1 cervix
cancer with no prior treatment or stage IIIA IIIC1 endometrial cancer status post
hysterectomy and lymph node assessment
- No required para aortic or extended field radiation
- Eastern Cooperative Oncology Group (ECOG) performance status 0 2
- Adequate kidney function (serum Cr <1.5 or creatinine clearance >50 mg/dl)
- Adequate bone marrow function (white blood cells > 3.0 X 109/L, platelets >100 x
109/L)
- Ability to understand and the willingness to sign a written informed consent document.
Exclusion Criteria:
- Treatment for other cancer in the past 2 years
- Previous pelvic radiation
- Medical condition that prevents receiving chemotherapy
Intervention(s):
diagnostic test: FDG PET/CT
drug: GCSF
Recruiting
I'm InterestedContact Information
Stanford University
School of Medicine
300 Pasteur Drive
Stanford,
CA
94305
Neha Aidasani
650-721-4076