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Breath Metabolomics in the Laboring Parturient
Not Recruiting
Trial ID: NCT04564196
Purpose
This is primarily a feasibility study to determine whether quantitative measurement of volatile organic compounds (VOCs) in the breath of parturients undergoing labor is possible.
Aim A: To determine baseline values of breath metabolites and volatile organic compounds (VOCs) in the breath for term pregnant women.
Aim B: To gather preliminary data to determine breath metabolite and volatile organic compound (VOCs) signature change during labor and delivery.
Aim C: Compare the breath metabolite and volatile organic compound (VOCs) signature women undergoing induction compared to spontaneous vaginal deliveries.
Official Title
Feasibility Study of the Collection of the Breath Metabolome From Healthy Parturients During Labor
Stanford Investigator(s)
Cedar Fowler
Clinical Assistant Professor, Anesthesiology, Perioperative and Pain Medicine
Pervez Sultan
Professor of Anesthesiology, Perioperative and Pain Medicine (Obstetrics)
Eligibility
Inclusion Criteria:
* Otherwise healthy nulliparous women with singleton term (37-41 weeks) pregnant at least 18 years of age.
* Presenting for labor (induction of labor and spontaneous labor) at LPHC.
Exclusion Criteria:
* Participants unable to or refuse to give informed consent
* Participants that do not understand English or are hearing impaired
* Medical History: Chronic disease (HTN, diabetes, asthma)
* Obstetric History during this pregnancy: gestational diabetes, gestational hypertension, pre-eclampsia, Eclampsia
* Multiple gestation
* Any significant fetal anomalies
* Morbid obesity (BMI\>50)
Intervention(s):
procedure: Breath Sample
Not Recruiting
Contact Information
Stanford University
School of Medicine
300 Pasteur Drive
Stanford,
CA
94305