Comprehensive Computed Tomography Guidance of Coronary Bypass Graft Surgery


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Trial ID: NCT03894423


Apply CT angiography, CT perfusion imaging and advanced image processing techniques to improve revascularization decision-making and surgical strategies in patients undergoing coronary artery bypass graft surgery.

Official Title

Comprehensive CT Guided Coronary Bypass Graft Surgery

Stanford Investigator(s)

Koen Nieman
Koen Nieman

Professor of Medicine (Cardiovascular Medicine) and of Radiology (CV Imaging)


Inclusion Criteria:

   - Planned elective CABG for coronary artery disease.

   - CABG is the primary indication for surgery (but may include treatment of mild-moderate
   valvular disease).

   - Age: ≥40 years.

Exclusion Criteria:

   - Technical feasibility of the cardiac CT exams: redo-CABG, significant
   arrhythmia/mal-conduction, congenital conditions, severe valvular disease or
   cardiomyopathy (to the extent that the CT acquisition is technically challenged),
   inadequate understanding of the English language (to provide consent or follow
   instructions during the exams).

   - Overall safety: unstable clinical condition (clinical heart failure, unstable angina,
   myocardial infarction <1 month prior).

   - Radiation risk: pregnancy (cannot be ruled out), body weight >100kg.

   - CT contrast medium-related: known allergy, renal failure

   - Vasodilator related: known allergy, bronchial asthma requiring daily use of
   bronchodilators, Mobitz II or 3rd degree AV block, sick sinus node disease, clinically
   significant carotid artery narrowing, severe aortic stenosis or LVOT narrowing,
   systolic blood pressure below 90mmHg, (continued) use of dipyridamole or

   - Inability to provide informed consent.


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Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Sarah Magee