Cycled Phototherapy


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Trial ID: NCT03927833


Cycled phototherapy (PT) is likely to increase survival over that with continuous PT among extremely premature infants (< 750 g BW or <27 weeks GA).

Official Title

Cycled Phototherapy: A Safer Effective Method to Control the Serum Bilirubin Of Extremely Premature Infants?

Stanford Investigator(s)


Inclusion Criteria:

   1. Infants is inborn

   2. Infant is ≤ 750 grams at birth and/or < 27 weeks gestation at birth by best OB

   3. Infant is 12-36 hours of age.

Exclusion Criteria:

   1. Unable to enroll infant by 36 hours of age

   2. Previous phototherapy

   3. Known hemolytic disease

   4. TSB reported as >6.0 mg/dL before 12 hours age

   5. Major anomaly

   6. Overt nonbacterial infection

   7. Infant is likely to expire soon: Limiting or withdrawal of intensive care is being
   recommended to the parents, the parents are requesting withdrawal of care, or the pH
   is < 6.80 or persistent bradycardia with hypoxemia for >2h.


device: Phototherapy lights


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Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
M. Bethany Ball