Comparative Effectiveness of Particulate Versus Nonparticulate Steroid Injections for Musculoskeletal Conditions

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Trial ID: NCT04278833

Purpose

This aims of this study are: 1. To determine if particulate or non-particulate corticosteroid injections are more effective at treating pain from musculoskeletal pathologies of the hip, glenohumeral joint, biceps tendon, or subacromial/subdeltoid bursa at 2 weeks, 3 months, or 6 months. 2. To determine if there is a significantly different side effect profile between particulate and non-particulate corticosteroids when used for hip, glenohumeral joint, biceps tendon, or subacromial/subdeltoid bursa injections.

Official Title

Comparative Effectiveness of Particulate Versus Nonparticulate Corticosteroid Injections for the Treatment of Musculoskeletal Conditions

Stanford Investigator(s)

Eugene Y. Roh, MD
Eugene Y. Roh, MD

Clinical Associate Professor, Orthopaedic Surgery

Eligibility


Inclusion Criteria:

   - Age greater than or equal to 18

   - Ability to provide informed consent

   - Capable of complying with the outcome instruments used

   - Capable of attending all planned follow up visits

   - Patient is deemed appropriate for intra-articular hip, glenohumeral, peri-tendinous
   biceps, or subdeltoid bursa corticosteroid injection by their treating physician for
   the treatment of painful musculoskeletal condition

   - Average pain of greater than or equal to 4/10 over the last 7 days

Exclusion Criteria:

   - Unclear diagnosis

   - Pregnancy

   - Incarcerated patients

   - Prior corticosteroid injection into the same anatomical site within the last 3 months

   - Prior prosthetic surgery on the joint

   - Any condition that increases injection risk such as bleeding tendencies, uncontrolled
   diabetes, current active infection, or infection requiring antibiotics within the last
   7 days

   - Chronic opioid use to control pain

   - Workers compensation and litigation

   - BMI > 40

Intervention(s):

drug: Triamcinolone or Betamethasone

drug: Dexamethasone

Recruiting

I'm Interested

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Agnes Martinez Ith
650-721-7600