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Confirming the Effectiveness of Online Guided Self-Help Family-Based Treatment for Adolescent Anorexia Nervosa
Trial ID: NCT05563649
With an incidence rate of about 1%, Anorexia Nervosa (AN) is a serious mental disorder associated with high mortality, morbidity, and cost. AN in youth is more responsive to early treatment but becomes highly resistant once it has taken an enduring course. The first-line treatment for adolescents with AN is Family Based Treatment (FBT). While FBT can be delivered using videoconferencing (FBT-V), therapists' limited availability hampers scalability. Guided self-help (GSH) versions of efficacious treatments have been used to scale and increase access to care. The main aim of this proposed comparative effectiveness study is to confirm that clinical improvements in GSH-FBT are achieved with greater efficiency than FBT-V in generalizable clinical settings.
Confirming the Effectiveness and Efficiency of Online Guided Self-Help Family-Based Treatment for Adolescent Anorexia Nervosa
1. Participants are 12-18 years of age
2. Participants live with a family (some families may contain only one parent)
3. Family members fluently speak and read English and have access to a computer with
4. Participants meet DSM-5 criteria for AN (both subtypes)
5. EBW between 75% and 88%
6. Participants are medically stable for outpatient treatment according to the
recommended thresholds of the American Academy of Pediatrics and the Society of
7. Participants are not engaged in another individual or family-based psychotherapy trial
during the duration of treatment sessions in the study.
8. Medications for comorbid psychiatric disorders are OK; randomization will balance
groups through tracking.
Current psychotic illness or mental retardation or other mental illnesses that would
prohibit the use of psychotherapy; current dependence on drugs or alcohol; physical
conditions (e.g. diabetes mellitus, pregnancy) known to influence eating or weight;
previous FBT; currently taking medication for co-morbid disorders that cannot be safely
discontinued or current dose has not been maintained for a minimum of 2 months; and
inability of the participant and/or family to speak and understand English.
behavioral: Online Guided Self-Help-Family-based Treatment
behavioral: FBT via Videoconferencing