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Development of 3DMPUS as a Decision Support Tool for Patients With Liver Tumors Undergoing Therapy
Not Recruiting
Trial ID: NCT05705219
Purpose
This clinical trial studies how well 3-dimensional multi-parametric ultrasound (3D MPUS)
imaging works as a decision-support tool for patients with liver tumors undergoing therapy.
Continuous and dynamic imaging of patients undergoing therapy is required to monitor
early-phase treatment response. 3D-MPUS is an inexpensive and safe method, which may provide
complementary quantitative functional (perfusion) and tissue characterization information to
anatomical radiological assessment or blood biomarkers.
Official Title
Development of 3DMPUS as a Decision Support Tool for Patients With Liver Tumors Undergoing Therapy
Stanford Investigator(s)
Aya Kamaya, MD
Professor of Radiology (Body Imaging)
Eligibility
Inclusion Criteria:
1. The participant is about to undergo a new course of therapy for primary or metastatic
liver cancer.
2. The participant is age > 18 years.
3. Participant has at least one target lesion (≥1cm and <14cm)
4. The participant is willing to comply with protocol requirements.
5. The participant has the ability to understand and the willingness to sign a written
informed consent document.
Exclusion Criteria:
1. Participant has documented anaphylactic or other severe reactions to any ultrasound or
CT contrast media.
2. Participant has documented severe Hypersensitivity to macrogol/ polyethylene glycol
(PEG).
3. Participant has documented the presence of a cardiac shunt or pulmonary hypertension
(pulmonary artery pressure >90 mmHg).
4. Participant has documented renal insufficiency with a creatinine level of >1.5mg/dl.
5. Participant has documented uncontrolled systemic hypertension.
6. Participant has documented concomitant diseases like acute endocarditis, prosthetic
valve, hyperactive coagulation states and/ or recent thromboembolism, and sepsis
7. Participant is pregnant (positive urine or serum beta-hCG) or lactating.
Intervention(s):
diagnostic test: 3D-MPUS
Not Recruiting
Contact Information
Stanford University
School of Medicine
300 Pasteur Drive
Stanford,
CA
94305
David Marcellus, BS
650-723-4547