Effect of Behavior Therapy on Responses to Social Stimuli in People With Social Phobia

Not Recruiting

Trial ID: NCT00380731


This study will evaluate the effect of cognitive behavioral therapy on the brain during emotional and behavioral responses to social stimuli in people with social phobia.

Official Title

fMRI of Emotional Reactivity Cognitive Regulation and CBT for Social Phobia

Stanford Investigator(s)


Inclusion Criteria:

   - Meets DSM-IV criteria for generalized social phobia

   - English-speaking

   - Eligible to participate in fMRI scanning

   - Willing to use an effective form of contraception throughout the study

Exclusion Criteria:

   - Currently undergoing any psychotherapy or pharmacotherapy (e.g, selective serotonin
   reuptake inhibitors, benzodiazepines, beta-blockers, anti-psychotics, blood thinners,
   thyroid hormone influencing agents, diabetic medications, or anticonvulsants)

   - History of neurological or cardiovascular disorders, brain surgery, electroconvulsive
   or radiation treatment, brain hemorrhage or tumor, stroke, seizures or epilepsy,
   diabetes, hypo- or hyperthyroidism, or head trauma with loss of consciousness for more
   than 5 minutes

   - Smokes cigarettes daily

   - History of or current diagnosis of schizophrenia, schizoaffective disorder, organic
   mental disorder, bipolar disorder, or antisocial, schizotypal, or schizoid personality

   - Suicidal thoughts

   - Clinically significant and/or unstable medical disease

   - Pregnant or breastfeeding

   - Alcohol or substance abuse or dependence within the 12 months prior to study entry

   - History of or current seizure disorder (except febrile seizure disorder during


behavioral: Individual Cognitive Behavioral Therapy

Not Recruiting

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Philippe Goldin