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Evaluation of a Closed-Loop Control System for Administering Patient-Specific Anesthesia
Not Recruiting
Trial ID: NCT00683956
Purpose
Numerous efforts have focused on the development of closed-loop systems to control anesthesia
using the electrical activity of the brain (EEG) and EEG-based parameters as surrogate
measures of anesthetic depth. New systems have been recently developed to considerably
improve anesthetic control using model-based, patient-adaptive methods. The purpose of this
study is to evaluate the clinical efficacy of a new intelligent software, ReinLoop, in
delivering closed-loop, patient-specific hypnosis.
Official Title
Evaluation of a Closed-Loop Control System for Patient-Specific Induction and Maintenance of Propofol Hypnosis
Stanford Investigator(s)
Anthony G. Doufas, M.D., Ph.D.
Professor of Anesthesiology, Perioperative and Pain Medicine
Eligibility
Inclusion Criteria:
1. 18-45 years of age
2. Body mass index (BMI) lower or equal to 25 m2/kg
3. Subjects must be able to comprehend spoken and written English
Exclusion Criteria:
1. Any type of psychiatric, neurological, or neuromuscular disorder
2. Thyroid disease
3. History of smoking
4. Alcohol consumption which exceeds 2 drinks per day and /or drug abuse. Volunteers will
be asked the question: How many drinks are you drinking on your typical day?
5. Allergy to study medication (propofol), soy, or egg proteins.
6. History of drug abuse
7. Chronic or acute use of opioids, or other medications affecting the CNS
8. Pregnancy
Intervention(s):
device: ReinLoop control software for patient-specific induction and maintenance of anesthesia
drug: Propofol
Not Recruiting
Contact Information
Stanford University
School of Medicine
300 Pasteur Drive
Stanford,
CA
94305