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Effects of an Herbal Topical Cream on Osteoarthritis Symptoms, Biomarkers, and Disease Progression in the Knee
Not Recruiting
Trial ID: NCT00800098
Purpose
Arthritis Relief Plus (ARP) Cream is a natural, herbal cream that has been shown to provide
pain relief and decreased stiffness. Anecdotal reports suggest that pain may continue to be
reduced months after cream use is stopped, indicating that there could be some
disease-modifying effects of the cream. The purpose of this study is to test the claim that
the ARP cream can provide long-term pain relief to osteoarthritis patients after only a short
period of use. The study will also try to determine whether the pain relief is accompanied
with any measurable indications that the progression of osteoarthritis has slowed or halted
Official Title
Effects of an Herbal Topical Cream on Osteoarthritis Symptoms, Biomarkers, and Disease Progression in the Knee
Stanford Investigator(s)
Garry Gold
Stanford Medicine Professor of Radiology and Biomedical Imaging
Eligibility
Inclusion Criteria:-Men and women between 40-70 years old
- Have a history of knee pain
- Exhibit mild osteoarthritis on the knee, as determined by Dr. Gold through MRIs and
radiographs (if available). Exclusion Criteria:-Outside of age range
- Prior knee surgery
- History of knee or knee ligament instability
- History of intermittent or persistent knee joint swelling
- History of trauma to the knee or lower extremities resulting in fracture, tears of
menisci, ligaments or joint capsule, or cartilage damage
- Unable to have MRI scan due to the presence of metallic internal devices that would
represent a risk factor for MRI and known or suspected pregnancy.
History of corticosteroid use
- Kidney Disease
- Knee diameter greater than 17cm and body diameter greater than 60 cm due to the
physical constraints of the MRI
Intervention(s):
drug: herbal topical cream
Not Recruiting
Contact Information
Stanford University
School of Medicine
300 Pasteur Drive
Stanford,
CA
94305
Jill Fattor, M.S.
650-721-4102