Emollient Therapy for Premature Infants in Zimbabwe

Not Recruiting

Trial ID: NCT05461404


The purpose of this study is to assess the efficacy of topical emollient treatments in improving neonatal growth and mortality rates.

Official Title

Emollient Therapy for Improved Survival and Growth of Very Low Birth Weight Infants in Zimbabwe

Stanford Investigator(s)


Inclusion Criteria:

   - infants <72 hours of age

   - weigh 700-1500 at birth

   - hospitalized at SMCH

Exclusion Criteria:

   - infants who are moribund and highly likely not to survive despite any intervention

   - significant breaches in their skin barrier

   - conditions indicating failure to gain weight

   - critically ill (definition below):

      1. Oxygen saturation <88% on oxygen therapy AND ≥2 of the following conditions:

      2. respiratory rate <20 or >100 breaths per minute

      3. apnea requiring bag-mask ventilation

      4. heart rate <100 or >200 beats per minute

   - congenital syphilis

   - hydrops fetalis

   - a life-threatening congenital anomaly or major surgical condition requiring

   - generalized skin disease or a structural defect involving >5% body surface area likely
   to produce a defect in epidermal barrier function


other: Topical Emollient Therapy

Not Recruiting

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Gary Darmstadt, MD, MS