Heparin and the Reduction of Thrombosis (HART) Trial

Not Recruiting

Trial ID: NCT00779558

Age - 1 Day-1 Year Condition - Pediatric Cardiology Gender - All Accepting Healthy Volunteers - No

Purpose

Heparin is frequently used in central venous catheters (CVCs) in post-operative cardiac patients. It remains unclear if a heparin infusion, compared to a normal saline infusion, prevents thrombosis of CVCs after surgery. This study will answer the question: does a low-dose heparin infusion (10 units/kg/h) prevent thrombosis, compared to a normal saline infusion, in patients less than one year of age after cardiac surgery?

Official Title

Heparin and Catheter-related Thrombosis in Neonates and Infants Following Cardiac Surgery

Stanford Investigator(s)

Stephen J. Roth

David M. Axelrod, MD

Eligibility


Inclusion Criteria:

   - All infants < 1 year of age undergoing cardiac surgery at Lucile Packard Children's
   Hospital & #xA

Exclusion Criteria:

   - Known coagulopathy

   - History of clinically significant bleeding (GI, cranial, pulmonary)

   - Need for therapeutic heparinization

   - ECMO

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Intervention(s):

drug: Heparin sulfate infusion at 10 units/kg/hour

drug: Placebo infusion

Not Recruiting

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
David Axelrod
4156072463

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