Heparin and the Reduction of Thrombosis (HART) Trial

Not Recruiting

Trial ID: NCT00779558


Heparin is frequently used in central venous catheters (CVCs) in post-operative cardiac patients. It remains unclear if a heparin infusion, compared to a normal saline infusion, prevents thrombosis of CVCs after surgery. This study will answer the question: does a low-dose heparin infusion (10 units/kg/h) prevent thrombosis, compared to a normal saline infusion, in patients less than one year of age after cardiac surgery?

Official Title

Heparin and Catheter-related Thrombosis in Neonates and Infants Following Cardiac Surgery

Stanford Investigator(s)


Inclusion Criteria:

   - All infants < 1 year of age undergoing cardiac surgery at Lucile Packard Children's
   Hospital & #xA

Exclusion Criteria:

   - Known coagulopathy

   - History of clinically significant bleeding (GI, cranial, pulmonary)

   - Need for therapeutic heparinization

   - ECMO


drug: Heparin sulfate infusion at 10 units/kg/hour

drug: Placebo infusion

Not Recruiting

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
David Axelrod