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Human Salivary Gland Disposition of Alda-341 in Patients Undergoing Salivary Gland Surgery
Not Recruiting
Trial ID: NCT04296266
Purpose
The purpose of this study is determine salivary gland disposition of d-limonene, the primary
component in citrus peel and a common dietary supplement.
Salivary gland tissue and saliva will be collected to determine concentration of d-limonene
and its metabolites in these tissues.
Official Title
Human Salivary Gland Disposition of Alda-341 in Patients Undergoing Salivary Gland Surgery
Stanford Investigator(s)
Quynh-Thu Le, MD
Katharine Dexter McCormick and Stanley McCormick Memorial Professor and Professor, by courtesy, of Otolaryngology - Head & Neck Surgery (OHNS)
Eligibility
Inclusion Criteria:
- Elected to undergo surgery for recent diagnosis of parotid or submandibular gland
tumor
- Ability to adhere to study visit schedule and other protocol requirements
- Operable candidate base on the surgeon's note
- Ability to understand and the willingness to sign a written informed consent document
Exclusion Criteria:
- Nursing or pregnant
- Diagnosis of kidney disease, history of renal disease with creatinine > 1.5 mg/dL, or
currently on dialysis
- Diagnosis of end stage liver disease
- Any unstable medical condition
- Use of chemotherapy or radiotherapy within 4 weeks before first dose of study dietary
supplement
- Unwilling to stop dietary supplements 3 weeks before first dose of study dietary
supplement
Intervention(s):
drug: Alda-341
Not Recruiting
Contact Information
Stanford University
School of Medicine
300 Pasteur Drive
Stanford,
CA
94305