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Imaging Kidney Transplant Rejection Using Ferumoxytol-Enhanced Magnetic Resonance
Trial ID: NCT02006108,25510
The goal of this study is to develop a non-invasive imaging test for in vivo detection of kidney transplant rejection. The hypotheses are that 1) Ferumoxytol-MRI can generate accurate estimates of tissue iron concentrations and tissue macrophages. 2) The signal given by a renal allograft on Ferumoxytol-MRI demonstrates significant differences between rejected and non-rejected transplants.
Non-invasive MR Imaging Diagnosis of Transplant Rejection
- Completed solid organ transplant with referral for transplant follow-up
- Exclusion criteria comprise MR-incompatible metal implants, need of sedation (since an
anesthesia is not supported by this), claustrophobia or hemosiderosis/hemochromatosis.
other: MRI-GE Healthcare 3 Tesla magnet
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