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Imaging Kidney Transplant Rejection Using Ferumoxytol-Enhanced Magnetic Resonance
Not Recruiting
Trial ID: NCT02006108
Purpose
The goal of this study is to develop a non-invasive imaging test for in vivo detection of kidney transplant rejection. The hypotheses are that 1) Ferumoxytol-MRI can generate accurate estimates of tissue iron concentrations and tissue macrophages. 2) The signal given by a renal allograft on Ferumoxytol-MRI demonstrates significant differences between rejected and non-rejected transplants.
Official Title
Non-invasive MR Imaging Diagnosis of Transplant Rejection
Stanford Investigator(s)
Heike Daldrup-Link
Professor of Radiology (General Radiology) and, by courtesy, of Pediatrics (Hematology/Oncology)
Eligibility
Inclusion Criteria:
* Completed solid organ transplant with referral for transplant follow-up
Exclusion Criteria:
* Exclusion criteria comprise MR-incompatible metal implants, need of sedation (since an anesthesia is not supported by this), claustrophobia or hemosiderosis/hemochromatosis.
Intervention(s):
drug: Feraheme
other: MRI-GE Healthcare 3 Tesla magnet
Not Recruiting
Contact Information
Stanford University
School of Medicine
300 Pasteur Drive
Stanford,
CA
94305
Anne Sawyer
650-302-2846