Imaging Kidney Transplant Rejection Using Ferumoxytol-Enhanced Magnetic Resonance

Not Recruiting

Trial ID: NCT02006108


The goal of this study is to develop a non-invasive imaging test for in vivo detection of kidney transplant rejection. The hypotheses are that 1) Ferumoxytol-MRI can generate accurate estimates of tissue iron concentrations and tissue macrophages. 2) The signal given by a renal allograft on Ferumoxytol-MRI demonstrates significant differences between rejected and non-rejected transplants.

Official Title

Non-invasive MR Imaging Diagnosis of Transplant Rejection

Stanford Investigator(s)

Heike Daldrup-Link
Heike Daldrup-Link

Professor of Radiology (General Radiology) and, by courtesy, of Pediatrics (Hematology/Oncology)


Inclusion Criteria:

   - Completed solid organ transplant with referral for transplant follow-up

Exclusion Criteria:

   - Exclusion criteria comprise MR-incompatible metal implants, need of sedation (since an
   anesthesia is not supported by this), claustrophobia or hemosiderosis/hemochromatosis.


drug: Feraheme

other: MRI-GE Healthcare 3 Tesla magnet

Not Recruiting

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Anne Sawyer