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©2022 Stanford Medicine
Not Recruiting
Trial ID: NCT02225730
Imaging Collaterals in Acute Stroke
Assistant Professor of Neurology and, by courtesy, of Neurosurgery
Clinical Associate Professor, Neurology & Neurological Sciences
Clinical Professor, Neurology & Neurological Sciences Clinical Professor (By courtesy), Neurosurgery
Professor of Radiology (Neuroimaging and Neurointervention)
Coyote Foundation Professor and Professor, by courtesy, of Neurosurgery
Professor of Neurology and, by courtesy, of Neurosurgery
Professor of Neurology and of Neurosurgery
Clinical Professor, Neurology & Neurological Sciences Clinical Professor (By courtesy), Neurosurgery
Inclusion Criteria
1. Age 18 and older
2. Clinical diagnosis of ischemic stroke and an associated score on the NIHSS of 5 or
more points
3. Planned to undergo (or has undergone) intra-arterial (IA) thrombectomy and/or
thrombolysis for acute hemispheric stroke. (Either as primary therapy or as adjuvant
therapy following intravenous tPA treatment)
4. Planned to undergo or has undergone an MR brain scan including MR perfusion imaging
(ASL & bolus PWI) and MR angiography of the circle of Willis prior to IA therapy
5. Intra-arterial thrombectomy can be started within 90 minutes of completion of the MR
perfusion scan and within 24 hours of symptom onset (Start of IA therapy is defined as
the time of insertion of the femoral artery sheath; Time of brain scan is defined as
the time that the scan is completed)
6. Able to obtain informed consent
Exclusion Criteria
1. Any pre-existing illness resulting in a modified Rankin Scale Score of 2 or higher
prior to the qualifying stroke
2. Creatinine clearance < 40 ml/min based on the NIDDK four-variable MDRD method
(non-weight based)
3. Documented allergy to MR contrast agent
4. MRI contraindications (pacemaker, etc.)
5. Pregnancy
Not Recruiting
Stanford University
School of Medicine
300 Pasteur Drive
Stanford,
CA
94305
Gregory Zaharchuk, MD
650-723-4448