Intraoperative Ketamine Versus Saline in Depressed Patients Undergoing Anesthesia for Non-cardiac Surgery

Not Recruiting

Trial ID: NCT03861988

Age - 18 Years-80 Years Gender - ALL Accepting Healthy Volunteers - No

Purpose

This study evaluates whether ketamine, given as part of an anesthetic, improves depression symptoms in depressed patients undergoing non-cardiac surgery. Half of participants will receive a ketamine infusion during surgery, while the other half will receive a placebo (normal saline) during surgery.

Official Title

Double-blind Trial of Intraoperative Ketamine Versus Saline in Depressed Patients Undergoing Anesthesia for Non-cardiac Surgery

Stanford Investigator(s)

Boris Heifets
Boris Heifets

Associate Professor of Anesthesiology, Perioperative and Pain Medicine (MSD) and, by courtesy, of Psychiatry and Behavioral Sciences (General Psychiatry and Psychology (Adult))

Eligibility

Inclusion Criteria:

* Patient presenting for non-cardiac, non-intracranial surgery
* Major Depressive Disorder

Exclusion Criteria:

* Pregnant of breastfeeding women

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Intervention(s):

drug: Ketamine

drug: Normal saline (placebo)

Not Recruiting

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Boris D Heifets, MD, PhD
917-620-4241

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