Intraoperative Ketamine Versus Saline in Depressed Patients Undergoing Anesthesia for Non-cardiac Surgery

Not Recruiting

Trial ID: NCT03861988

Age - 18 Years-80 Years Gender - All Accepting Healthy Volunteers - No

Purpose

This study evaluates whether ketamine, given as part of an anesthetic, improves depression symptoms in depressed patients undergoing non-cardiac surgery. Half of participants will receive a ketamine infusion during surgery, while the other half will receive a placebo (normal saline) during surgery.

Official Title

Double-blind Trial of Intraoperative Ketamine Versus Saline in Depressed Patients Undergoing Anesthesia for Non-cardiac Surgery

Stanford Investigator(s)

Boris Heifets
Boris Heifets

Assistant Professor of Anesthesiology, Perioperative and Pain Medicine (Adult MSD) and, by courtesy, of Psychiatry and Behavioral Sciences

Eligibility


Inclusion Criteria:

   - Patient presenting for non-cardiac, non-intracranial surgery

   - Major Depressive Disorder

Exclusion Criteria:

   - Pregnant of breastfeeding women

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Intervention(s):

drug: Ketamine

drug: Normal saline (placebo)

Not Recruiting

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Boris D Heifets, MD, PhD
917-620-4241

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