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Not Recruiting
Trial ID: NCT04406584
Intranasal Injection of Platelet-rich Plasma Versus Saline for Treatment of Olfactory Dysfunction
Professor of Otolaryngology - Head & Neck Surgery (OHNS)
Inclusion Criteria:
- Patients >= 18 years of age
- Patients who have olfactory loss (based off of UPSIT score <= 33 out of 40)
- Patients who also have an age-adjusted TDI Sniffin' Sticks score that demonstrates
hyposmia (TDI>16 and <30)
- Etiology of olfactory loss is due to URI or idiopathic
- At least 6 months of olfactory loss but less than 12 months
- Patients can have been previously treated with oral and topical steroids but this is
not a requirement
- Patients will receive concurrent olfactory training - the practice of smelling strong
odors (standard of care)
- Be able to read and understand English
- Agree to participate in the study
- Be able and willing to provide Informed Consent
Exclusion Criteria:
- Patients < 18 years of age
- Pregnant females
- Patient who have any structural abnormalities on nasal endoscopy or radiographic
imaging
- Olfactory loss due to trauma, chronic sinusitis / inflammation / polyps, neoplasms, or
neurodegenerative diseases
- Patients who have had olfactory loss > 12 months
- Patients with bleeding disorders or on blood thinners such as coumadin and plavix
procedure: Injection into olfactory cleft
Not Recruiting
Stanford University
School of Medicine
300 Pasteur Drive
Stanford,
CA
94305
Zara M Patel, MD
650-723-5651