Incidental Coronary Calcification Quality Improvement Project

Not Recruiting

Trial ID: NCT04789278

Purpose

This is a multi-center, randomized quality improvement project. At least 200 statin-naïve patients without a history of atherosclerotic cardiovascular disease with incidental coronary artery calcium (CAC) on a prior non-gated chest CT will be enrolled across the Stanford Healthcare System and the Palo Alto Veteran's Affairs Healthcare System. Patients will be randomized in a 1:1 fashion to notification or usual care arms. The primary aim of this project is to estimate the increase in 6-month statin prescription among statin-naïve patients without a history of atherosclerotic cardiovascular disease with incidental CAC on a non-gated chest CT who are randomized to receive notification of their findings vs. usual care.

Official Title

Incidental Coronary Calcification Quality Improvement Project

Stanford Investigator(s)

Alexander Tarlochan Singh Sandhu
Alexander Tarlochan Singh Sandhu

Assistant Professor of Medicine (Cardiovascular Medicine)

Eligibility

Inclusion Criteria:

* Non-gated chest CT between 2014-2019
* The presence of CAC confirmed by manual review by an experienced radiologist
* Stanford affiliated primary care provider or endocrinologist for Stanford healthcare system patients and VA primary care provider for VA patients with at least 1 encounter since 2018

Exclusion Criteria:

* Current or prior statin or PCSK9 inhibitor therapy
* Prior diagnosis of ASCVD (coronary artery disease, peripheral arterial disease, cerebrovascular disease, coronary/peripheral revascularization)
* Prior coronary imaging (cardiac CT, invasive coronary angiography)
* Dementia
* Metastatic cancer or active cancer undergoing chemotherapy
* History of medical nonadherence

Intervention(s):

other: Notification

Not Recruiting

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305