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Identifying Risk Factors That Predict Onset of Anorexia Nervosa and Bulimia Nervosa
Recruiting
I'm InterestedTrial ID: NCT05133037
Purpose
Across the United States, thousands of children and adolescents suffer from eating disorders. Among young women alone, an estimated 2 to 4 percent are dealing with anorexia nervosa. Anorexia nervosa also has the highest mortality rate of any psychiatric disorder and produces a six-fold increased risk for death. Unfortunately, study shows that current treatments are only successful with 25 percent of patients and no eating disorder prevention program has been found to reduce future onset of anorexia nervosa. The goal of this study is to conduct a highly innovative pilot study that will identify risk factors that predict future onset of anorexia nervosa and investigate how the risk processes for anorexia nervosa are different from the risk processes for bulimia nervosa. The proposed pilot study will:
* Compare 30 healthy adolescent girls at high risk for anorexia nervosa to 30 healthy adolescent girls at high risk for bulimia nervosa, and 30 healthy adolescent girls at low risk for eating disorder in an effort to document risk processes that are present in early adolescence before anorexia nervosa typically emerges.
* Test whether elevations in the hypothesized risk factors predict future onset of anorexia nervosa over a four-year follow-up.
Official Title
Identifying Risk Factors That Predict Onset of Anorexia Nervosa and Bulimia Nervosa
Stanford Investigator(s)
Eligibility
Inclusion Criteria:
* Female
* Ages 12 - 16
* Must have biological parental history of AN or BN, or no history of psychiatric diagnoses
Exclusion Criteria:
* Current diagnosis of an Eating Disorder;
* Symptoms of major psychiatric disorders (substance use disorders, conduct disorder, attention deficit hyperactive disorder, major depression, bipolar disorder, panic disorder, agoraphobia, generalized anxiety disorder);
* Serious medical conditions (diabetes, brain injury, cancer);
* Body Mass Index (BMI) \<17.5;
* Any contraindications for MRI (e.g. metal objects/implants in body, irremovable body piercings, tattoos or braces, medications that interfere with MRI, history of head injury with loss of consciousness, phobia that wouldn't allow them to complete the MRI);
* Current regular psychoactive drug use;
* Relevant food allergies;
* Not in age range
Recruiting
I'm InterestedContact Information
Stanford University
School of Medicine
300 Pasteur Drive
Stanford,
CA
94305
Laura Rubino
650-549-4829