Multiomic Signatures of Microbial Metabolites Following Prebiotic Fiber Supplementation

Not Recruiting

Trial ID: NCT03925597

Age - 18 Years-99 Years Gender - ALL Accepting Healthy Volunteers - yes

Purpose

The investigators propose a comprehensive, multiomic study that will integrate longitudinal data associating changes in specific gut bacteria and host in response to prebiotic fiber supplementation. These data will guide the development of an integrative biological signature relating bacterial-derived metabolites with biological outcome in the host. The open sharing of data generated by the proposed research represents a significant public resource that will support and accelerate future novel studies.

Official Title

Multiomic Signatures of Microbial Metabolites Following Prebiotic Fiber Supplementation

Stanford Investigator(s)

Michael Snyder, Ph.D.

Eligibility

Inclusion Criteria:

\- good general health

Exclusion Criteria:

* Chronic inflammatory conditions
* Major organ disease
* Heavy alcohol use
* Pregnancy/lactation
* Use of medication known to affect carbohydrate or lipid metabolism
* Active eating disorder

View More
View Less

Intervention(s):

dietary_supplement: Fiber cycles ARM 1

dietary_supplement: Fiber cycles ARM 2

dietary_supplement: Fiber cycles ARM 3

dietary_supplement: Fiber cycles ARM 4

dietary_supplement: Fiber cycles ARM 5

dietary_supplement: Fiber cycles ARM 6

dietary_supplement: Fiber cycles ARM 7

dietary_supplement: Fiber cycles ARM 8

dietary_supplement: Fiber cycles ARM 9

dietary_supplement: Fiber cycles ARM 10

dietary_supplement: Fiber cycles ARM 11

dietary_supplement: Fiber cycles ARM 12

dietary_supplement: Fiber cycles ARM 13

dietary_supplement: Fiber cycles ARM 14

dietary_supplement: Fiber cycles ARM 15

dietary_supplement: Fiber cycles ARM 16

dietary_supplement: Fiber cycles ARM 17

dietary_supplement: Fiber cycles ARM 18

dietary_supplement: Fiber cycles ARM 19

dietary_supplement: Fiber cycles ARM 20

dietary_supplement: Fiber cycles ARM 21

dietary_supplement: Fiber cycles ARM 22

dietary_supplement: Fiber cycles ARM 23

dietary_supplement: Fiber cycles ARM 24

Not Recruiting

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Dalia Perelman
650-569-0462

©2025 Stanford Medicine