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©2022 Stanford Medicine
Not Recruiting
Trial ID: NCT01050647
Progesterone for the Management of Preterm, Premature Rupture of the Membranes: A Randomized Controlled Trial.
Charles B. and Ann L. Johnson Professor in the School of Medicine and Professor, by courtesy, of Pediatrics (Neonatology) and of Surgery
Inclusion Criteria:
1. 18yr of age
2. Singleton pregnancy
3. PPROM confirmed on clinical exam
4. GA between 24+0 and 33+5 wk
5. Ability to understand consent in either English or Spanish
Exclusion Criteria:
1. Contraindication to ongoing pregnancy including:
1. Evidence of active infection
2. Evidence of significant placental abruption
3. IUFD diagnosed at the time of P-PROM diagnosis
2. Major fetal malformation
3. Maternal allergy to progesterone or placebo drug components
4. Current use of progesterone at the time of P-PROM
5. Multiple Gestations
6. Inability to understand consent in either English or Spanish
other: Caster Oil injections
drug: 17-Hydroxyprogesterone Caproate
Not Recruiting
Stanford University
School of Medicine
300 Pasteur Drive
Stanford,
CA
94305
Cynthia Willson, RN
650-724-6372