©2024 Stanford Medicine
Pharmacokinetics of Ketamine in Infants and Children
Not Recruiting
Trial ID: NCT01100138
Purpose
Dosing of medications is based on the plasma level achieved with a given dose and how long the medicine remains in the body. This study is called pharmacokinetics-that is, what the body does to the medication. Ketamine is an intravenous medication used for anesthesia and sedation in children. However the pharmacokinetics of Ketamine has not been systematically studied. We propose to study the pharmacokinetics of ketamine in different age groups of children ranging from infants to teenagers.
Official Title
Pharmacokinetics of Ketamine in Infants and Children
Stanford Investigator(s)
Chandra Ramamoorthy
Professor of Anesthesiology, Perioperative and Pain Medicine (Pediatric), Emerita
Eligibility
Inclusion Criteria:
* Term infants (38 weeks gestation)and infants and children up to age 18 years.
* Patients who require procedures that necessitate at least 8 hours in the hospital and those being admitted after procedure will be eligible to participate.
* Patients who will receive ketamine as part of their standard anesthesia regimen.
Exclusion Criteria:
* Preterm neonates
* Liver Disease
* Kidney disease
* Heart failure
* Sepsis
* Patients receiving anticonvulsants or barbiturates
Intervention(s):
drug: ketamine hydrochloride
Not Recruiting
Contact Information
Stanford University
School of Medicine
300 Pasteur Drive
Stanford,
CA
94305
Archana Verma
6507211713