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Perfusion CT as a Predictor of Treatment Response in Patients With Rectal Cancer
Not Recruiting
Trial ID: NCT01460641
Purpose
A research study of rectal cancer perfusion (how blood flows to the rectum over time). We
hope to learn whether perfusion characteristics of rectal masses may be predictive of
response to treatment and whether rectal perfusion characteristics can be used to follow
response to treatment.
Official Title
Perfusion CT as a Predictor of Treatment Response in Patients With Rectal Cancer
Stanford Investigator(s)
Uri Ladabaum
Professor of Medicine (Gastroenterology and Hepatology)
Subhas Banerjee
Professor of Medicine (Gastroenterology and Hepatology)
Daniel Rubin
Professor of Biomedical Data Science and of Radiology (Integrative Biomedical Imaging Informatics at Stanford), of Medicine (Biomedical Informatics Research) and, by courtesy, of Ophthalmology and of Computer Science
Andrew A. Shelton, MD, FACS, FACRS
Clinical Professor, Surgery - General Surgery
George A. Fisher Jr.
Colleen Haas Chair in the School of Medicine
Teri A Longacre
Richard L. Kempson, MD, Professor in Surgical Pathology
Dominik Fleischmann
Professor of Radiology (Cardiovascular Imaging)
Eligibility
Inclusion Criteria:
- Patients with suspected or biopsy-proven, locally advanced rectal cancer will be
eligible for enrollment.
- Patients must be 18 years or older. Patients must not be pregnant and, if of
child-bearing age, must take precautions not to become pregnant.
- No life expectancy restrictions.
- ECOG and Karnofsky Performance Status will not be employed.
- Patients with renal failure are ineligible for this study (GFR must be > 60)
- Ability to understand and willingness to sign a written informed consent document.
Exclusion Criteria:
- Patients who have undergone prior treatment for rectal cancer are ineligible for
enrollment.
- No restrictions regarding use of other investigational agents.
- Patients with severe contrast allergy are ineligible.
- Patients who are pregnant or are trying to become pregnant are excluded from this
study.
- Patients who are cancer survivors or HIV-positive will not be excluded.
Not Recruiting
Contact Information
Stanford University
School of Medicine
300 Pasteur Drive
Stanford,
CA
94305
Laura Gable
650-736-0798