Prospective Validation of Cough, Dyspnea, and Quality of Life Questionnaires in Patients With IPF

Not Recruiting

Trial ID: NCT01874223

Purpose

The purpose of this study is to test cough, dyspnea (shortness of breath), and quality of life (QOL) questionnaires for their accuracy, sensitivity, and ability to reliably measure the severity of cough, breathlessness, and changes in cough and disease-related quality of life over time in Idiopathic Pulmonary Fibrosis (IPF) patients. These questionnaires have been used in other types of disease, but have not all been tested and validated in patients with cough due to IPF. Our hypothesis is that worsening of cough, dyspnea, and cough-related QOL questionnaire scores will correlate with physiologic markers of IPF severity and worsening of disease. Written, valid questionnaires measuring cough, dyspnea, and QOL are important to assess the benefit of investigational drugs under development to treat patients with IPF.

Official Title

Prospective Validation of Cough, Dyspnea, and Quality of Life Questionnaires in Patients With Idiopathic Pulmonary Fibrosis (IPF)

Stanford Investigator(s)

Rishi Raj
Rishi Raj

Clinical Professor, Medicine - Pulmonary, Allergy & Critical Care Medicine

Eligibility

Inclusion Criteria:

* Completion of informed consent.
* Adults over the age of 18.
* Diagnosis of IPF per ATS guidelines.
* Clinically stable at the time of enrollment defined as no antibiotics within the past month, with the exception of those patients currently listed for Lung Transplantation.
* No changes in immunosuppressive regimens (if applicable) over past month.

Exclusion Criteria:

* Inability to understand or complete paper and pencil questionnaires.
* Patient not planning to return to Stanford for clinic visits.

Not Recruiting

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Susan S Jacobs, RN, MS