Pediatric ACL: Understanding Treatment Options


Trial ID: NCT02772770


Pediatric ACL: Understanding Treatment Outcomes (PLUTO) is a multi-center, prospective cohort study. Specific aims of PLUTO are to evaluate the safety and comparative effectiveness of non-operative treatment, as well as four operative treatments including (1) transphyseal ACL reconstruction (2) partial transphyseal ACL reconstruction, (3) physeal-sparing epiphyseal ACL reconstruction using the Anderson technique, and (4) physeal-sparing ACL reconstruction using the Micheli/Kocher technique in prepubescent and pubescent skeletally immature patients.

Official Title

Pediatric ACL: Understanding Treatment Options (PLUTO)

Stanford Investigator(s)

Kevin Shea

Chambers-Okamura Endowed Professor of Pediatric Orthopaedics


Inclusion Criteria:

   - Diagnosis of complete intrasubstance ACL tear

   - Skeletally Immature (by knee radiographs)

Exclusion Criteria:

   - Prior ACL surgery on the ipsilateral knee

   - Congenital ACL deficiency

   - Multiple ligament reconstruction required

   - Other significant comorbidities including syndromic conditions, neuromuscular
   disorders or developmental delay

   - If scheduling of the ACL surgery is impacted by the skeletal maturity of the patient

   - Simultaneous bilateral ACL tears


other: Non-operative treatment group will undergo standardized treatment which will include rehabilitation, bracing and certain activity restrictions

procedure: Surgical technique: Transphyseal reconstruction

procedure: Surgical technique: Partial transphyseal reconstruction

procedure: Surgical technique: Physeal sparing reconstruction by the Anderson method

procedure: Surgical technique: Physeal sparing reconstruction by the Micheli/Kocher method


Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Steven Frick, MD